Tuffy Mouse is the main protagonist from Tom and Jerry short cartoons and films.
A young baby light-grey, white diaper-wearing mouse.
- Jerry and Cherie's nephew, Tom, Tyke and Quacker's friend, Uncle Pecos and Harry's grandnephew, Muscles' cousin, Mrs. Mouse's grandson, Geraldine's son, Lucy's boyfriend and the Mouse Queen's little fiancé and a good friend of Troops the blue-uniformed soldiers.
- Kath Soucie.
- Tara Strong.
- Samuel Vincent.